Metabolic syndrome ?? ????? ???? ?????? ??? 3
More studies are needed to understand the relationship between metabolic risk factors and the efficacy of drug therapy in people who have the metabolic syndrome. To gain the most benefit from modifying multiple metabolic risk factors, the underlying insulin-resistant state must become a target of therapy. The safest, most effective and preferred way to reduce insulin resistance in overweight and obese people is weight loss and increased physical activity. Other steps for managing the metabolic syndrome are also important for patients and their doctors: Routinely monitor body weight (especially the index for central obesity), blood glucose, lipoproteins and blood pressure. Treat individual risk factors (hyperlipidemia, hypertension and high blood glucose) according to established guidelines. Carefully choose anti-hypertensive drugs because different agents have different effects on insulin sensitivity.